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DAT (chemotherapy)
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DAT (chemotherapy) : ウィキペディア英語版
DAT (chemotherapy)
DAT in the context of chemotherapy is an acronym that means a chemotherapy regimen most often used as an induction regimen in acute myelogenous leukemia, usually for those who are refractory to the standard "7+3" induction regimen or who has relapsed. But this regimen also can be used as primary, first-line induction therapy.
The DAT regimen consists of:
# (D)aunorubicin - an anthracycline antibiotic that is able to intercalate DNA, thus disrupting cell division and preventing mitosis;
# (A)ra-C (cytarabine) - an antimetabolite;
# (T)hioguanine - another antimetabolite.〔(Randomized Comparison of DAT Versus ADE as Induction Chemotherapy in Children and Younger Adults With Acute Myeloid Leukemia. Results of the Medical Research Council's 10th AML Trial (MRC AML10) )〕
== Dosing regimen ==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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